Calcium antagonists, nitrates, and new antianginal drugs.
نویسندگان
چکیده
منابع مشابه
INIew Drugs Calcium antagonists , nitrates , and new antianginal drugs
Considerable progress in the medical as well as the surgical management of angina has been made in the past decade. An appreciation of the pharmacokinetics of the "oldest" antianginal drugs, the nitrates, has lead to the development of effective long acting preparations and novel techniques of administration. On the other hand, calcium antagonists represent a new approach to the treatment of an...
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chest pain group. 3) Effective treatment: The efficacy of three standard antianginal drugs on silent myocardial ischemia was studied in 43 patients with EA using Holter monitoring. Antianginal drugs used were long-acting isosorbide dinitrate 40-80 mg/day for nitrates (17 patients), diltiazem 90-180 mg/day for calcium antagonists (13 patients), propranolol 30-60 mg/day or metoprolol 60-120 mg/da...
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The influence of several calcium antagonists and antiarrhythmic drugs on digoxin kinetics and actions were investigated in 36 healthy men during digoxin steady state (0.375 mg/day). The subjects were randomly assigned to three subgroups and each group received placebo (control) and two of the following regimens (doses three times a day) in a randomized sequence for 2 wk each: verapamil (80 mg) ...
متن کاملAn evaluation of beta-blockers, calcium antagonists, nitrates, and alternative therapies for stable angina.
Searching MEDLINE (from 1966 to 1997) and EMBASE (from 1974 to 1997) were searched for publications in the English language using the following search criteria: MeSH term 'angina pectoris' or the textword 'angina', and publication type 'randomized controlled trial' or textword containing a form of the word 'random'. The authors also performed searches using publication type 'controlled clinical...
متن کاملMeta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina.
CONTEXT Which drug is most effective as a first-line treatment for stable angina is not known. OBJECTIVE To compare the relative efficacy and tolerability of treatment with beta-blockers, calcium antagonists, and long-acting nitrates for patients who have stable angina. DATA SOURCES We identified English-language studies published between 1966 and 1997 by searching the MEDLINE and EMBASE da...
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ژورنال
عنوان ژورنال: BMJ
سال: 1983
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.286.6371.1127